Before the work on intermittent fasting, the only real strategy for extending the lives of laboratory animals was caloric restriction (CR). If rats or mice or even primates had their calories restricted by 30-40 percent as compared to those fed ad libitum [“at pleasure” = as much as they want] they lived 20-30 percent longer.
These CR verses ad libitum-fed studies almost uniformly demonstrate an increase in longevity in the CR animals. The CR animals not only live 30 percent or so longer, they don’t develop cancers, diabetes, heart disease, or obesity. And these animals have low blood sugar levels, low insulin levels, good insulin sensitivity, low blood pressure and are, in general, much healthier physically than their ad libitum fed counterparts.Real Life Extension: Caloric Restriction or Intermittent Fasting? (Part 1)
Covered by ABC News today!